Secretin Endoscopic Pancreatic Function Test
- ePFT is safe easy and highly accurate
- Cost effective 30% lower than traditional testing
Can be utilized in almost all facilities that provide endoscopic procedures
Gastrinoma Testing (Zollinger-Ellison Syndrome Test)
- Is the most sensitive and accurate diagnosing method
- A simple blood test, easily performed in an office setting
- Reliably differentiates patients with Gastrinomas and peptic ulcer disease, even in the presence of acid blockers
- Any increase in serum gastrin concentration > 110 pg/mL above baseline is a diagnosis of Zollinger- Ellison Syndrome
- Highly purified synthetic peptide
- Not manufactured by a recombinant process
- ChiRhoStim® is identical to naturally occurring Human Secretin
- Less chance of allergic reaction
To perform a Zollinger-Ellison Syndrome Test follow this procedure:
- The patient should have fasted for at least 12 hours prior to beginning the test.
- Prior to injection of ChiRhoStim® (Human Secretin for injection), two blood samples are drawn for determination of fasting serum gastrin levels (baseline values).
- Administer ChiRhoStim® (Human Secretin for injection) at a dose of 0.4 mcg/kg of body weight is injected intravenously over 1 minute;
- Post-injection blood samples are collected after 1, 2, 5, 10, and 30 minutes for determination of serum gastrin concentrations.
- Gastrinoma is strongly indicated in patients who show an increase in serum gastrin concentration of at least 110 pg/mL over basal level on any of the post secretin injection samples.
ChiRhoStim Human Secretin for Injection can be used to diagnose Zollinger-Ellison (Z-E) syndrome; diagnose gastrinoma.
Gastrin >110 pg/mL with gastric acid hypersecretion (basal acid secretion >15 mmol/hour in a patient with peptic ulcer who has not had surgery) establishes unequivocally the diagnosis of the Zollinger-Ellison syndrome.4 Antral G-cell hyperplasia may relate to high gastrin levels and duodenal ulcer.